Keratin Hair Booster Men [TESTING]

Further information can be found here.

The body produces vitamin D3 (cholecalciferol) itself with the help of sunlight. Vitamin D deficiency is the most common vitamin deficiency in our latitudes: around half of the population does not achieve sufficient vitamin D levels - especially in winter and when there is little sunlight.

The diet (e.g. fatty fish, eggs) usually only provides small amounts. Older people, people with little sun exposure, vegans and vegetarians are particularly at risk. Supplementing with vitamin D can therefore be useful for many people.

Vitamin D contributes to the normal function of the immune system, it plays a decisive role in the absorption of calcium and phosphorus to maintain normal bones and teeth and it also supports normal muscle function.

Scientific studies are also looking at the influence of vitamin D on mood and the course of chronic diseases. An increasing number of scientific studies are also looking at the connection between vitamin D and the growth of our hair and various causes of hair loss.

In randomized studies and meta-analyses, vitamin D3 reliably raises blood levels (25-OH vitamin D) - often more than vitamin D2. The bodily functions mentioned have been scientifically proven and are recognized by regulators. The appropriate dosage remains important: too high a long-term intake can increase the calcium balance - regardless of the source of the D3.

Our OrgaVitaz D3® is vegan and lanolin-free. Our vitamin D3 is extracted exclusively with natural solvents. The clear specification and standardized amounts of vitamin D3 ensure reliable quality. In short: OrgaVitaz D3® combines plant origin with reliable standardization for high-quality vitamin D3 supplementation.

Vitamin D₂ vs. D₃
Tripkovic L, Lambert H, Hart K, et al. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. Am J Clin Nutr. 2012;95(6):1357-1364. doi:10.3945/ajcn.111.031070. 

Heaney RP, Davies KM, Chen TC, Holick MF, Barger-Lux MJ. Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. Am J Clin Nutr. 2003;77(1):204-210. doi:10.1093/ajcn/77.1.204. 

Vitamin D und CVD/Krebs, Gesamtmortalität

Manson JE, Cook NR, Lee IM, et al.; VITAL Research Group. Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease. N Engl J Med. 2019;380(1):33-44. doi:10.1056/NEJMoa1809944. 
Neale RE, Baxter C, Romero BD, et al. The D-Health Trial: a randomised controlled trial of the effect of vitamin D on mortality. Lancet Diabetes Endocrinol. 2022;10(2):120-128. doi:10.1016/S2213-8587(21)00345-4. 
Scragg R, Stewart AW, Waayer D, et al. Effect of Monthly High-Dose Vitamin D Supplementation on Cardiovascular Disease in the ViDA Study: A Randomized Clinical Trial. JAMA Cardiol. 2017;2(6):608-616. doi:10.1001/jamacardio.2017.0175. 

Vitamin D und Knochen
LeBoff MS, Chou SH, Ratliff KA, et al. Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults. N Engl J Med. 2022;387(4):299-309. doi:10.1056/NEJMoa2202106. 
Sanders KM, Stuart AL, Williamson EJ, et al. Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial. JAMA. 2010;303(18):1815-1822. doi:10.1001/jama.2010.594. 
Bolland MJ, Grey A, Avenell A. Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis. Lancet Diabetes Endocrinol. 2018;6(11):847-858. doi:10.1016/S2213-8587(18)30265-1.
Reid IR, Bolland MJ, Grey A. Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis. Lancet. 2014;383(9912):146-155. doi:10.1016/S0140-6736(13)61647-5. 
Trivedi DP, Doll R, Khaw KT. Effect of four-monthly oral vitamin D₃ supplementation on fractures and mortality in community-dwelling adults: RCT. BMJ. 2003;326(7387):469-471. doi:10.1136/bmj.326.7387.469. 

Vitamin D und Atemwegsinfekte (ARI)
Martineau AR, Jolliffe DA, Hooper RL, et al. Vitamin D supplementation to prevent acute respiratory tract infections: IPD meta-analysis. BMJ. 2017;356:i6583. doi:10.1136/bmj.i6583. 
Pham H, Waterhouse M, Baxter C, et al. Effect of vitamin D supplementation on ARI in older adults: analysis from D-Health. Lancet Diabetes Endocrinol. 2021;9(2):69-81. doi:10.1016/S2213-8587(20)30380-6. 

Vitamin D und Stimmung/Depression
Okereke OI, Reynolds CF 3rd, Mischoulon D, et al. Long-term Vitamin D₃ vs placebo and risk of depression: RCT (VITAL-DEP). JAMA. 2020;324(5):471-480. doi:10.1001/jama.2020.10224. 

Vitamin D und Haare
Chen Y, Dong X, Wang Y, Li Y, Xiong L, Li L. Serum 25-hydroxyvitamin D in non-scarring alopecia: a systematic review and meta-analysis. J Cosmet Dermatol. 2024;23(4):1131-1140. doi:10.1111/jocd.16093.
Yongpisarn T, Tejapira K, Thadanipon K, Suchonwanit P. Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis. Front Nutr. 2024;11:1479337. doi:10.3389/fnut.2024.1479337.
Hassan GFR, Sadoma MET, Elbatsh MM, Ibrahim ZA. Treatment with oral vitamin D alone, topical minoxidil, or combination of both in patients with female pattern hair loss: a comparative clinical and dermoscopic study. J Cosmet Dermatol. 2022;21(9):3917-3924. doi:10.1111/jocd.14743.
El-Tatawy RA, Gheida S, Soliman GAM, Ismail M. Oral Vitamin D treatment in patients with telogen effluvium: clinical and dermoscopic evaluation. Int J Trichology. 2023;15(5):183-190. doi:10.4103/ijt.ijt_92_22.
Sattar F, Almas U, Ibrahim NA, Akhtar A, Shazad MK, Akram S, et al. Efficacy of oral Vitamin D3 therapy in patients suffering from diffuse hair loss (telogen effluvium). J Nutr Sci Vitaminol (Tokyo). 2021;67(1):68-71. doi:10.3177/jnsv.67.68.

Banihashemi M, Nahidi Y, Meibodi NT, Jarahi L, Dolatkhah M. Serum vitamin D3 level in patients with female pattern hair loss. Int J Trichology. 2016;8(3):116-120. doi:10.4103/0974-7753.188965.

Nayak K, Garg A, Mithra P, Manjrekar P. Serum vitamin D3 levels and diffuse hair fall among the student population in South India: a case-control study. Int J Trichology. 2016;8(4):160-164. doi:10.4103/ijt.ijt_57_16.

Ali S, Collins M, Pupo Wiss I, Senna M. Vitamin D deficiency among patients with lichen planopilaris or frontal fibrosing alopecia. JAAD Int. 2022;8:109-110. doi:10.1016/j.jdin.2022.05.010.

Arasu A, Meah N, Eisman S. Vitamin D status in patients with frontal fibrosing alopecia: a retrospective study. JAAD Int. 2022;7(4):129-130. doi:10.1016/j.jdin.2022.03.008.

Demay MB. The hair cycle and vitamin D receptor. Arch Biochem Biophys. 2012;523(1):19-21. doi:10.1016/j.abb.2011.10.002.

Joko Y, Yamamoto Y, Kato S, Takemoto T, et al. VDR is an essential regulator of hair follicle regression through the progression of cell death. Life Sci Alliance. 2023;6(11):e202302014. doi:10.26508/lsa.202302014.

Vegesna V, O’Kelly J, Uskokovic M, Said J, Lemp N, Saitoh T, et al. Vitamin D3 analogs stimulate hair growth in nude mice. Endocrinology. 2002;143(11):4389-4396. doi:10.1210/en.2002-220118.

Palmer HG, et al. The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and cycling. PLoS One. 2008;3(11):e1483. doi:10.1371/journal.pone.0001483.

Karat TP, Bains A, Bhardwaj A, Singh S, Budania A, Patra S, et al. Comparing the efficacy of combined intralesional triamcinolone acetonide with topical calcipotriol versus intralesional triamcinolone acetonide monotherapy in scalp and beard alopecia areata: results from a randomized single-blinded clinical trial. J Cutan Med Surg. 2025;29(4):355-361. doi:10.1177/12034754251316303.

El Taieb MA, Hegazy EM, Ibrahim HM, Osman AB, Abualhamd M. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial. Arch Dermatol Res. 2019;311(8):629-636. doi:10.1007/s00403-019-01961-4.

Wellmune® is a highly pure β-1,3/1,6-glucan from the cell wall of baker's yeast (Saccharomyces cerevisiae). It is one of the best-studied β-glucans and has been described in numerous human studies as supporting the immune system during periods of stress and strain.

After ingestion, Wellmune® reaches the intestine, where it is absorbed by macrophages in the gut-associated immune system (GALT) - one of the body's largest immune organs. These immune cells process the β-glucan particles and pass on signals to other defense cells. In this way, the natural immune response is modulated and supported.

In studies, Wellmune® showed fewer colds and fewer sick days. It also supports us in challenging phases of everyday life against stress and fatigue, and it restores the immune balance more quickly after sport and exertion.

Not all β-glucans are the same. Efficacy is highly dependent on source, structure and purity. In a comparative study, Wellmune® showed the highest activity in the immune system compared to other commercially available β-glucans from yeast, fungi or oats. This makes Wellmune® one of the leading immune raw materials worldwide, which is supported by numerous clinical studies.

Human and basic studies on Wellmune®
Talbott SM, Talbott JA. Baker's yeast beta-glucan supplement reduces upper respiratory symptoms and improves mood state in stressed women. J Am Coll Nutr. 2012;31(4):295-300. doi:10.1080/07315724.2012.10720441.
McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(2):171-183. doi:10.3109/19390211.2013.820248.
Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast β-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl. 2020;17(2):200-210. doi:10.1080/19390211.2018.1495676.
Fuller R, Moore MV, Lewith G, Stuart BL, Ormiston RV, Fisk HL, et al. Yeast-derived β-1,3/1,6 glucan, upper respiratory tract infection and innate immunity in older adults. Nutrition. 2017;39-40:30-35. doi:10.1016/j.nut.2017.03.003.
Hong F, Yan J, Baran JT, Allendorf DJ, Hansen RD, Ostroff GR, et al. Mechanism by which orally administered β-1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models. J Immunol. 2004;173(2):797-806. (Demonstrates macrophage uptake and signal transduction.)
Williams DL, Mueller A, Browder IW. Glucan-based macrophage stimulators: a review of their anti-infective potential. Clin Immunother. 1996;5(5):392-399. (Basic principles of macrophage uptake and immune activation).
Jesenak M, Majtan J, Rennerova Z, Kyselovic J, Banovcin P, Hrubisko M. Immunomodulatory effect of pleuran (β-glucan from Pleurotus ostreatus) in children with recurrent respiratory infections. Int Immunopharmacol. 2013;15(2):395-399. (Comparative studies on different β-glucans; Wellmune showed strongest activity in independent studies).

Turmeric (Curcuma longa) is a spice and cultivated plant from the ginger family. It has been valued for many centuries in Ayurveda and traditional Chinese medicine. Originally native to India, the majority of turmeric is still grown there today and processed as "Indian gold".

The bright yellow color of turmeric comes from the curcuminoids - primarily curcumin, as well as demethoxy- and bisdemethoxycurcumin. In the scientific literature, curcuminoids are primarily studied for their antioxidant properties and in connection with inflammatory processes.

Due to its special properties, curcumin occupies a prominent position among plant extracts worldwide.

Unformulated, "natural" curcumin from the turmeric plant is poorly absorbed by the body: It hardly dissolves in the aqueous intestinal environment, is unstable at a neutral-basic pH value and the small amount absorbed is rapidly glucuronidated/sulphated in the intestine and liver - in other words "masked" to a certain extent. These conjugated forms are significantly less cell-permeable.

Longvida® Curcumin belongs to the modern 3rd generation formulations. The decisive difference: it brings free (non-masked) curcumin into the bloodstream.Bioavailability is increased by a lecithin-based lipid matrix (micelle-like solubilization) that protects curcumin in the digestive tract and improves absorption - without piperine and without synthetic polysorbates such as Tween 80. Although piperine (black pepper) is often used as a bioavailability booster, it inhibits enzymes and transporters that can break down or transport drugs. Longvida® achieves high bioavailability without piperine.

Studies: Longvida® Curcumin is supported by numerous human studies - including on cognitive parameters & mood, stress/regeneration markers in sport and joint comfort.

Klinische Studien (Menschen) – Longvida®/SLCP
Gota VS, Maru GB, Soni TG, Gandhi TR, Kochar N, Agarwal MG. Safety and Pharmacokinetics of a Solid Lipid Curcumin Particle Formulation in Osteosarcoma Patients and Healthy Volunteers. J Agric Food Chem. 2010;58(4):2095‑2099. doi:10.1021/jf9024807. American Chemical Society PublicationsEurope PMC

DiSilvestro RA, Joseph E, Zhao S, Bomser J. Diverse effects of a low dose supplement of lipidated curcumin in healthy middle‑aged people. Nutr J. 2012;11:79. doi:10.1186/1475‑2891‑11‑79. (Verwendet Longvida®; 400 mg Pulver/Tag mit 80 mg Curcumin.) BioMed Central

Cox KHM, Pipingas A, Scholey AB. Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population. J Psychopharmacol. 2015;29(5):642‑651. doi:10.1177/0269881114552744. (400 mg Longvida®.) PubMed


McFarlin BK, Venable AS, Henning AL, et al. Reduced inflammatory and muscle damage biomarkers following oral supplementation with bioavailable curcumin. BBA Clin. 2016;5:72‑78. doi:10.1016/j.bbacli.2016.02.003. (Longvida® 400 mg/Tag.) PubMed

Gupte PA, Giramkar SA, Harke SM, et al. Evaluation of the efficacy and safety of Capsule Longvida® Optimized Curcumin (solid lipid curcumin particles) in knee osteoarthritis: a pilot clinical study. J Inflamm Res. 2019;12:145‑152. doi:10.2147/JIR.S205390. PMC

Cox KHM, White DJ, Pipingas A, Poorun K, Scholey A. Further Evidence of Benefits to Mood and Working Memory from Lipidated Curcumin in Healthy Older People: A 12‑Week, Double‑Blind, Placebo‑Controlled, Partial Replication Study. Nutrients. 2020;12(6):1678. doi:10.3390/nu12061678. (Longvida® 400 mg/Tag.) PubMed

Gimblet CJ, Kruse NT, Geasland K, et al. Curcumin Supplementation and Vascular and Cognitive Function in Chronic Kidney Disease: A Randomized Controlled Trial. Antioxidants (Basel). 2024;13(8):983. doi:10.3390/antiox13080983. (Longvida® 2000 mg/Tag; primäre Endpunkte neutral.) PubMed




Sicherheit & Pharmakokinetik (Longvida®/SLCP)
Dadhaniya P, Patel C, Muchhara J, et al. Safety assessment of a solid lipid curcumin particle preparation: acute and subchronic toxicity studies. Food Chem Toxicol. 2011;49(8):1834‑1842. PubMed
Phipps KR, Keefer K, Seidel B, Chell CJ. Safety assessment of a solid lipid curcumin particle preparation: In vitro and in vivo genotoxicity studies. J Appl Toxicol. 2023;43(6):e14434. doi:10.1002/jat.4434. (Longvida® nicht genotoxisch.) PubMed

Kroon MAGM, Berbee JK, Majait S, et al. A pharmacokinetic study and critical reappraisal of curcumin formulations enhancing bioavailability. iScience. 2025;(online). doi:10.1016/j.isci.2025.112575. (Crossover‑PK; u. a. Longvida®; unabhängige Bewertung.) ScienceDirectPubMed


Präklinische/Mechanistische Studien (Longvida®/SLCP)
Ullah F, Nahar L, et al. Effects of a solid lipid curcumin particle formulation on chronic glial activation and neurodegeneration in GFAP‑IL6 mice. Sci Rep. 2020;10: Article 58838. doi:10.1038/s41598‑020‑58838‑2. (Longvida®/LC.) NaturePubMed

Gharaibeh A, Maiti P, Culver R, et al. Solid Lipid Curcumin Particles Protect Medium Spiny Neuronal Morphology, and Reduce Learning and Memory Deficits in the YAC128 Mouse Model of Huntington’s Disease. Int J Mol Sci. 2020;21(24):9542. doi:10.3390/ijms21249542. (SLCP ≙ Longvida®.) MDPI

Nahar PP, Slitt AL, Seeram NP. Anti‑Inflammatory Effects of Novel Standardized Solid Lipid Curcumin Formulations. J Med Food. 2015;18(7):786‑792. doi:10.1089/jmf.2014.0053. (In‑vitro; SLCP/Longvida®.) PMC

Transparenzhinweis: Eine frühere Alzheimer‑Mausarbeit mit SLCP (Maiti et al., 2018, BMC Neuroscience) wurde 2023 zurückgezogen und ist hier daher nicht berücksichtigt. BioMed Central+1

Belege zu Piperin (Bioverfügbarkeit ≠ risikofrei)
Bhardwaj RK, Glaeser H, Becquemont L, et al. Piperine, a major constituent of black pepper, inhibits human P‑glycoprotein and CYP3A4. J Pharmacol Exp Ther. 2002;302(2):645‑650. PubMed

Health Canada – Monograph „Black pepper (Piper nigrum)“. Vorgabe: isoliertes Piperin ≤ 14 mg/Tag. (Sicherheits‑/Kombinationshinweise für Natural Health Products.) Aktualisiert 2024. webprod.hc-sc.gc.ca+1

Ziegenhagen R, et al. Safety Aspects of the Use of Isolated Piperine Ingested as a Single Substance—A Statement of the BfR. 2021. (Zusammenfassung der Sicherheitsbewertung inkl. 14‑mg‑Grenze für isoliertes Piperin.) PMC

Lin F, Yamada S, et al. Predicting Food–Drug Interactions between Piperine and CYP3A4 Substrate Drugs Using PBPK Modeling. Pharmaceutics. 2024;(online). (Modellierung potenzieller Interaktionen über CYP3A4‑Hemmung.)


Astaxanthin is a bright red-orange, natural pigment and belongs to the carotenoids - like beta-carotene, lycopene or lutein. It is produced in the microalgae Haematococcus pluvialis, among others.

The algae uses it to protect itself from oxidative damage caused by UV rays. In nature, astaxanthin can also be found in the orange coloration of salmon, krill or flamingos - because they ingest the algae directly or indirectly through their food. As a raw material, astaxanthin is preferably obtained from H. pluvialis.

Astaxanthin is one of the most powerful natural antioxidants. It is being studied scientifically primarily because of its antioxidant properties. Human studies have investigated skin parameters (e.g. elasticity, moisture, reaction to UV influences), the influence on oxidative stress at the hair root, aspects of the immune system, markers of performance/regeneration in sport, vision/visual fatigue and markers of lipid metabolism.

ASTAFIT® is a natural astaxanthin from H. pluvialis. The algae are cultivated in Austria (Styria/Hartberg) in closed photobioreactors; the astaxanthin is then gently extracted using CO₂ extraction, among other methods.

The result is a standardized quality as a water-dispersible, highly bioavailable astaxanthin powder, designed for versatile applications in food supplements.In short: ASTAFIT® combines natural tradition with state-of-the-art cultivation in Austria - reliably standardized for premium products.

Astaxanthin in the skin / photoprotection
Tominaga K, Hongo N, Karato M, Yamashita E. Cosmetic benefits of astaxanthin on human subjects. Acta Biochim Pol. 2012;59(1):43-47. (Open-label + RCT; 6 mg/d; skin wrinkles, TEWL, elasticity).
Ito N, Seki S, Ueda F. The Protective Role of Astaxanthin for UV-Induced Skin Deterioration-A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2018;10(7):817. (9 wo.; UV-induced skin reaction).
Ng QX et al. Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review. J Diet Suppl. 2021;18(2):169-182. (Multiple RCTs; texture, wrinkles, hydration).
Astaxanthin in the eyes
Saito M et al. Astaxanthin increases choroidal blood flow velocity. Graefes Arch Clin Exp Ophthalmol. 2012;250:239-245. (RCT; 12 mg/d; 4 weeks).
Sekikawa T et al. Effects of diet containing astaxanthin on visual function in healthy individuals. Nutrients. 2022 (Review/overview; incl. human studies on "eye fatigue").
Astaxanthin and immune system
Park JS, et al. Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans. Nutrition & Metabolism. 2010;7:18.
Nieman DC,et al. Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins. Frontiers in Nutrition. 2023;10:1143385.

Astaxanthin for athletes and regeneration
Brown DR et al. The effect of astaxanthin supplementation on performance in cyclists. J Sci Med Sport. 2021 (crossover; 12 mg/d, 7 days; 40-km TT).
Tsao JP et al. Short-term astaxanthin enhanced endurance performance (young adults). BMC Sports Sci Med Rehabil. 2025 (crossover RCT).
Astaxanthin and lipid/antioxidant markers (human)
Yoshida H et al. Administration of natural astaxanthin increases serum HDL-cholesterol and decreases triglycerides. Atherosclerosis. 2010;209(2):520-523. (RCT).
Nakagawa K et al. Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes. Br J Nutr. 2011;105(11):1563-1571. (RCT; 6/12 mg/d; 12 wk).
Heidari M et al. A randomized, double-blind, placebo-controlled clinical trial in CAD patients: Lipid parameters. Front Nutr. 2023.
Overviews / Classification Astaxanthin
Villaró S et al. Microalgae-derived astaxanthin - research & consumer aspects. Mar Drugs / Appl Sci. 2021 (open access review).